@article{Gomaa_Barakat_Salama_El Gohary_2022, title={Assessment of antibacterial genes of emerging queen Apis mellifera L. induced by the bacterium Paenibacillus larvae larvae}, volume={30}, url={https://www.africanentomology.com/article/view/13586}, DOI={10.17159/2254-8854/2022/a13586}, abstractNote={<p>This study evaluated the expression of antimicrobial abaecin and defensin genes in virgin honey-bee queens (<em>Apis mellifera</em>) following induction of 4th larval instar with the bacterium <em>Paenibacillus larvae</em> larvae (1.07 × 10<sup>2</sup> CFU/queen); to investigate whether the presence of bacteria affects the immune response as well as gene transcript levels for the immune proteins. The total body proteins of bacteria-treated queens showed a highly significant increase, and the appearance of new proteins patterns and/or disappearance of others. The gene expression profile of treated queens showed up-regulation equalled four-fold of the defensin gene, whereas no progression occurred in the abacien gene. This finding likewise greatly affects the diseases challenging this pollinator.</p>}, journal={African Entomology}, author={Gomaa, SAS and Barakat, EMS and Salama, MS and El Gohary, EE}, year={2022}, month={Sep.} }